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Date:         Wed, 30 Nov 2011 19:10:53 -0800
Reply-To:     "Jordan, Lewis" <Lewis.Jordan@WEYERHAEUSER.COM>
Sender:       "SAS(r) Discussion" <SAS-L@LISTSERV.UGA.EDU>
From:         "Jordan, Lewis" <Lewis.Jordan@WEYERHAEUSER.COM>
Subject:      Re: Unable to fit the model with PROC NLIN
Comments: To: SUBSCRIBE SAS-L Anonymous <rkbattula@DRREDDYS.COM>
In-Reply-To:  <>
Content-Type: text/plain; charset="us-ascii"

P.S. Get rid of the derivatives statement. NLIN is now smart enough that it can compute these for you...

***************************** Lewis Jordan Weyerhaeuser: Southern Timberlands Group Cell (Primary): 662-889-4514 Office: 662-245-5227 ***************************** ________________________________________ From: SAS(r) Discussion [SAS-L@LISTSERV.UGA.EDU] On Behalf Of SUBSCRIBE SAS-L Anonymous [rkbattula@DRREDDYS.COM] Sent: Wednesday, November 30, 2011 3:45 AM To: SAS-L@LISTSERV.UGA.EDU Subject: Unable to fit the model with PROC NLIN

Hi every body,

I tried to fit the model with three observations. I have three different doses and their PD responses. I used following code:

proc nlin data = it method=marquardt hougaard; parms E0 =1 ED50 =1 Emax = 1 ; parameters; model FFEP=E0 + ((Emax * Dose) / (ED50 + Dose)); Der.E0 = 1; Der.Emax = Dose / ( ED50 + Dose); Der.ED50 = - (( Emax * Dose)/ ((ED50 + Dose)**2)); output out=pred p=yhat; run;

Model is not able to fit since I have only three observations. Is there any way to work on this? Your help is greatly appriciated.



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