Date:         Mon, 11 Aug 2008 09:42:28 -0400
Reply-To:     Kevin Viel <citam.sasl@GMAIL.COM>
Sender:       "SAS(r) Discussion" <SAS-L@LISTSERV.UGA.EDU>
From:         Kevin Viel <citam.sasl@GMAIL.COM>
Subject:      Re: GLIMMIX - Obtain Adjusted Odds Ratio?

On Sat, 9 Aug 2008 07:55:16 -0700, Ryan <Ryan.Andrew.Black@GMAIL.COM> wrote:

>Thank you for responding! I'm sorry for taking so long to reply. I
>didn't realize anyone responded! My primary goal is to obtian the odds
>of contracting disease 1 to the odds of contracting disease 2, after
>controlling for x1.
>
>I completely understand, and agree that disease_indicator*x1 will not
>provide me with the odds ratio of interest. However, if I requested
>the odds ratio for the estimates, I should obtain an odds ratio
>for:"disease_indic." Would this odds ratio not tell me the odds of
>contracing one disease to the odds of contracting another disease,
>after controlling for the effects of the covariate for each disease.
>If not, then how would you obtain this odds ratio. The whole point of
>this analysis is to simply compare the odds of contracting one disease
>to the odds of contracting another one, AFTER evening the playing
>field with repsect to x1. I'd really love to hear your thoughts, if
>you have the time to respond.

OK, this is starting to bother me a bit so I think I will ask for come
clarification.  Please describe the hypothesis, the study design, and
emphasize the sampling technique.

I think clarifying the outcome is important.  Is one disease of greater
interest?  Does your study population start disease free?  Importantly, is
one disease a consequence of the other?  Can the sequence of the outcomes
of the disease be identified?  Is the time to events important, especially
between infections?  Could this be handle with survival analysis and time-
varying covariates?

I guess I am particular cautious of the interactions in the model as
formulated.  Maybe I missed something?

Kevin