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Date:         Fri, 30 May 2008 21:16:12 -0500
Reply-To:     paul@WUBIOS.WUSTL.EDU
Sender:       "SAS(r) Discussion" <SAS-L@LISTSERV.UGA.EDU>
From:         Paul Thompson <paul@WUBIOS.WUSTL.EDU>
Subject:      Re: modelling lactation curves
Comments: To: Kanagasabai Nadarajah <nadarka@AUBURN.EDU>
In-Reply-To:  <484062FD020000E70008CB91@GWACES2.DUC.AUBURN.EDU>
Content-Type: text/plain; charset=ISO-8859-1; DelSp="Yes"; format="flowed"

Quoting Kanagasabai Nadarajah <nadarka@AUBURN.EDU>:

> Fitting various type of models and procedures to predict lactation > curves have been extensively studied by animal scientists. > This paper compares many options and covers other work too. > > Models for Estimating Typical Lactation Curves in Dairy Cattle > C.U. Leon-Velarde,, I. McMillan, R.D. Gentry and J.W. Wilton > J. Anim. Breed. Genet. (1995) 112:333-340 > > Nada

THanks for this. It really did sound way too obvious that no one would have tried a quadratic model before. Plenty of sharp people in animal sciences. That is the real discipline in which mixed models of certain types were first developed.

> > > Nada K. Nadarajah, PhD > Senior Research Fellow > Dept. of Animal Sciences. > Auburn University. > Auburn, AL 36849-5415 > Tel: 334-844-1502 > Fax: 334-844-1519 > URL: http://www.ag.auburn.edu/ansc/staff/nada.html > >>>> Peter Flom <peterflomconsulting@mindspring.com> 05/30/08 7:48 PM >>> >> >> milk production follows a curve, as some of you may already now. When >> a high producer cow calves, the milk production per day is aroung 10 >> kg a day, but increases very quickly getting soon a peak (even more >> than 40 kg/day) and then it starts decreasing slowly. >> I have seen paper that compare the milk production between two >> treatments by using PROC MIXED and REPEATED. >> >> For instance: >> >> proc mixed; >> class cow treatment; >> model production = treatment day treatment*day; >> repeated /subject=cow type=cs; *they usually try different types to >> see which one fits better; >> run; >> >> However, to me, that is not totally sound, since milk production is >> not linear. >> Is there any way to overcome this problem? Is it going to make any >> difference in the results? >> > > > Paul made the excellent suggestion of centering and then fitting a > quadratic. However, even this may fit your curve adequately. With > independent data, I'd suggest a spline, but, AFAIK, this isn't available > in MIXED. You might be able to do something in NLMIXED (and Dale may be > chiming in with much better advice), but how many time points do you > typically have? If it's more than (say) 20 per cow, have you considered > some form of time series analysis? > > Peter > > Peter L. Flom, PhD > Statistical Consultant > www DOT peterflom DOT com >


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