Date:         Wed, 21 May 2008 19:00:35 -0400
Reply-To:     Sigurd Hermansen <HERMANS1@WESTAT.COM>
Sender:       "SAS(r) Discussion" <SAS-L@LISTSERV.UGA.EDU>
From:         Sigurd Hermansen <HERMANS1@WESTAT.COM>
Subject:      Re: Phase 1 (Oncology)
In-Reply-To:  <6237a86e-c77c-4098-8f83-3af8ccd18e04@56g2000hsm.googlegroups.com>
Content-Type: text/plain; charset="us-ascii"

   1.Is it the SAS Programmer who decide Maximum Tolerable Dose(MTD) and
Dose Limiting Toxicity by
      using the SAS reports?

   I would certainly hope not! ... unless, that is, you are talking
about the MTD and Dose Limiting Toxicity of the SAS reports themselves
;>
S

-----Original Message-----
From: owner-sas-l@listserv.uga.edu [mailto:owner-sas-l@listserv.uga.edu]
On Behalf Of Al
Sent: Wednesday, May 21, 2008 2:25 PM
To: sas-l@uga.edu
Subject: Phase 1 (Oncology)


Hi
                  I am woking on Phase1(oncology) and i have few
questions
   1.Is it the SAS Programmer who decide Maximum Tolerable Dose(MTD) and
Dose Limiting Toxicity by
      using the SAS reports?

   2.For example if a Patient gets say dose 5.0 (day1 day2 and day3) on
visit1 and  dose 6.0 (day1 , day2 and day3) on visit2 and
     again dose 5.0(day1 day2 and day3 ) on visit3
    which category of doses(5 or 6) this  patient fall under if i were
to code a demog table by dose

   If any one of you has worked on phase 1 dose escalation
protcols.Please provide me some insights

   Thanks in advance