Date: Tue, 6 Jun 2006 15:02:32 -0400
Reply-To: Kevin Roland Viel <kviel@EMORY.EDU>
Sender: "SAS(r) Discussion" <SAS-L@LISTSERV.UGA.EDU>
From: Kevin Roland Viel <kviel@EMORY.EDU>
Subject: Re: Clinical Trial Ns for Multiple Arms
Content-Type: TEXT/PLAIN; charset=US-ASCII
On Tue, 6 Jun 2006, firstname.lastname@example.org wrote:
> I have a general question about multiple arm studies, specifically when a
> patient switches doses --how to count the Ns. It seems that if a subject
> switches doses, that the subject should be counted in each treatment group.
> Is there a standard for this such that the subject is counted in each dosage
> the subject is on vs. the Ns are the same for each dose (thus reflecting the
> overall Number of Subjects (regardless of dose)?
> Any information on this is appreciated.
Have you considered an "intention to treat" analysis? Under this
scenario, the treatment arm into which you randomly assigned the subject
is the analyses group regardless of treatment.
Department of Epidemiology
Rollins School of Public Health
Atlanta, GA 30322