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Date:         Tue, 20 Dec 2005 15:16:58 -0800
Reply-To:     David L Cassell <davidlcassell@MSN.COM>
Sender:       "SAS(r) Discussion" <SAS-L@LISTSERV.UGA.EDU>
From:         David L Cassell <davidlcassell@MSN.COM>
Subject:      Re: Cox model assumption check
In-Reply-To:  <200512201450.jBKBk8u1012059@mailgw.cc.uga.edu>
Content-Type: text/plain; format=flowed

statsas@GMAIL.COM wrote: >I need to check the assumption of Cox model for the treatment group, >which is the main variable of interest, and there are also quite a lot >covariates in the data set. The follow-up time (survival time) is days >from randomization to either diagnosis of disease or censoring. > >Is there a way that I can perform this assumption check in SAS? I >thought I can do a plot of residual of survivial time against time? >Will this work? > >I appreciate any input from you folks!!!

Before I get to PROC PHREG, I usually check the proportional hazards assumption using PROC LIFETEST.

If the proportional hazards assumptionl is appropriate, then the estimates of the log(-log(estimated survival distribution)) plotted against the log(TIME) should be parallel lines. If the Weibull model is a good fit, then these lines should be pretty straight too. If you have SAS 9.1 then you can plot this out using ODS Statistical Graphics.

HTH, David -- David L. Cassell mathematical statistician Design Pathways 3115 NW Norwood Pl. Corvallis OR 97330

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